Wolkers, Willem F.

Wolkers, Willem F., Prof. PhD


REBIRTH Unit Biostabilization of tissues and macromolecular assemblies

Leibniz University of Hanover
Callinstr. 36
30167 Hannover


Biography / About

Date of Birth:August, 1966
Function:Group leader


09/1986 – 09/1992MSc (Ir.), Molecular Sciences, Wageningen University, Netherlands
01/1994 – 05/1998PhD (Dr.), Dept. of Plant Physiology, Wageningen University, Netherlands

Academic appointments and Research posts:

06/1998 – 06/1999Research Scientist, Quadrant Healthcare, Cambridge, UK
10/1998 – 12/2003Group leader, Department of Molecular and Cellular Biology, University of California, Davis, CA, USA
09/2004 – 12/2004Lecturer, Laboratoire de Génie et Microbiologie des Procédé Alimentaires, Institut National de la Recherche Agronomique, Thiverval-Grignon, France
01/2005 – 10/2005Senior scientist, Sanquin Bloodbank, Amsterdam, Netherlands
11/2005 – 10/2007Senior scientist, Department of Mechanical Engineering, University of Minnesota, Minneapolis, MN, USA
12/2006Appointment research assistant professor
11/2007 – 10/2011Provisional leader Professorship (W3), Institute of Multiphase Processes, Leibniz Universität Hannover, Hannover, Germany
11/2011Appointment Professor (W3)

Other professional activities:

  • Society for Cryobiology (board of governors, editorial board)
  • Transfusion Medicine and Hemotherapy (editorial board)
  • Society for Low Temperature Biology

Major research interests:

  • Cryobiology
  • Freeze-drying
  • Membrane biophysics
  • Protein stability
  • Tissue engineering

Selected Publications:

  1. Zhang M, Oldenhof H, Sieme H, Wolkers WF, Freezing-induced uptake of trehalose into mammalian cells facilitates cryopreservation. Biochim Biophys Acta1858 (2016) 1400-1409.
  2. Wang S, Oldenhof H, Dai X, Haverich A, Hilfiker A, Harder M, Wolkers WF, Sucrose diffusion in decellularized heart valves for freeze-drying. Tissue Eng Part C 21 (2015) 922-931.
  3. Wang S, Oldenhof H, Dai X, Haverich A, Hilfiker A, Harder M, Wolkers WF, Protein stability in stored decellularized heart valve scaffolds and diffusion kinetics of protective molecules. Biochim Biophys Acta 1844 (2014) 430–438.
  4. Wang S, Goecke T, Meixner C, Haverich A, Hilfiker A, Wolkers WF, Freeze-dried heart valve scaffolds. Tissue Eng Part C 18 (2012) 517-525.
  5. Sánchez V, Redmann K, Wistuba J, Wübbeling F, Burger M, Oldenhof H, Wolkers WF, Kliesch S, Schlatt S, Mallidis C, Oxidative DNA damage in human sperm can be detected by Raman microspectroscopy. Fertility and Sterility 98 (2012) 1124-1129.
  6. Akhoondi M, Oldenhof H, Stoll C, Sieme H, Wolkers WF, Membrane hydraulic permeability changes during cooling of mammalian cells. Biochim Biophys Acta 1808 (2011) 642–648.
  7. Stoll C, Stadnick H, Kollas O, Holovati JL, Glasmacher B, Acker JP, Wolkers WF, Liposomes alter thermal phase behavior of red blood cell membranes. Biochim Biophys Acta 1808 (2011) 474-481.
  8. Oldenhof H, Friedel K, Sieme H, Glasmacher B, Wolkers WF, Freezing-induced membrane phase changes and water transport in Stallion sperm: A Fourier transform infrared spectroscopy study. Cryobiology 61 (2010) 115–122.
  9. Shah N, Wolkers WF, Morrissey M, Sun WQ, Bischof JC, FTIR Investigation of native tissue matrix modifications by gamma irradiation process. Tissue Eng Part C 15 (2009) 33-40.
  10. Wolkers WF, Balasubramanian SK, Ongstad EL, Zec H, Bischof JC, Effects of freezing on membranes and proteins in LNCaP prostate tumor cells. Biochim Biophys Acta 1768 (2007) 728-736.

[zurück zur Liste]
Diese Webseite verwendet Cookies und die Webanalyse-Software Google Analytics. Klicken Sie hier für weitere Informationen zum Datenschutz.