REBIRTH Mitglieder

Dräger, Gerald

Dräger, Gerald, Dr. rer. nat.

Arbeitsgruppenleiter

REBIRTH Unit Functionalized Polymers and Regenerative Agents

Leibniz University of Hannover, Institut für Organische Chemie
Schneiderberg 1b
30167 Hannover

draeger(at)oci.uni-hannover.de

Biography / About

Date of Birth:October, 1968
Function:Junior leader / academic director

Education:

1989 – 1997Technical University of Clausthal (Major: Organic Chemistry)
1994Diploma examination; “Synthese glycosylierter Decarestrictine” (Synthesis of glycosylated decarestrictins)
1997 Ph.D. examination, Advisor: Prof. Andreas Kirschning; „Synthesen desoxygenierter Glycokonjugate und Analoga” (Synthesis of deoxygenated glycoconjugates and analogues)

Academic appointments and Research posts:

1995 – 1996Research stay at the University of Göttingen, Institute of Organic Chemistry
1997 – 1998Postdoctorial position at the University of Washington, Department of Chemistry (Seattle, WA, USA), Advisor: Prof. Dr. H. G. Floss; ”Genetical and chemical exploration of the biosynthesis of the 2,6-dideoxyhexose moiety in granaticin”
Since 2000Independent research at the Institute of Organic Chemistry of the University Hannover (Germany) and head of the center for mass spectrometry

Other professional activities:

1999 – 2000Research chemist at the AnalytiCon AG in Potsdam/Berlin (Germany)
2009 – 2014CEO of the Centre of Biomolecular Drug Research (BMWZ)

Major research interests:

  • Hydrogels
  • Biopolymers
  • Surface chemistry
  • Nanoparticles
  • Small molecule synthesis

Selected Publications:

  1. Dibbert N, Krause A, Rios-Camacho J-C, Gruh I, Kirschning A, Dräger G. A Synthetic Toolbox for the In Situ Formation of Functionalized Homo- and Heteropolysaccharide-Based Hydrogel Libraries. Chemistry 2016; 22(52):18777–86.
  2. Dahlmann J, Krause A, Möller L, Kensah G, Möwes M, Diekmann A, Martin U, Kirschning A, Gruh I, Dräger G. Fully defined in situ cross-linkable alginate and hyaluronic acid hydrogels for myocardial tissue engineering. Biomaterials 2013; 34(4):940–51.
  3. Möller L, Hess C, Paleček J, Su Y, Haverich A, Kirschning A, Dräger G. Towards a biocompatible artificial lung: Covalent functionalization of poly(4-methylpent-1-ene) (TPX) with cRGD pentapeptide. Beilstein J Org Chem 2013; 9:270–7.
  4. Su Y, Paleček J, Kirschning A, Dräger G. Copper Mediated and Copper Free “Click” Decoration of Polysialic Acid for RGD-Modification and Hydrogel Formation. Macromol. Symp. 2013; 334(1):82–91.
  5. Krause A, Kirschning A, Dräger G. Bioorthogonal metal-free click-ligation of cRGD-pentapeptide to alginate. Org. Biomol. Chem. 2012; 10(29):5547–53.
  6. Möller L, Krause A, Bartsch I, Kirschning A, Witte F, Dräger G. Preparation and In Vivo Imaging of Lucifer Yellow Tagged Hydrogels. Macromol. Symp. 2011; 309-310(1):222–8.
  7. Möller L, Krause A, Dahlmann J, Gruh I, Kirschning A, Dräger G. Preparation and evaluation of hydrogel-composites from methacrylated hyaluronic acid, alginate, and gelatin for tissue engineering. IJAO 2011; 34(2):93–102.
  8. Paleček J, Dräger G, Kirschning A. A Practical Large-Scale Synthesis of Cyclic RGD Pentapeptides Suitable for Further Functionalization through ‘Click' Chemistry. Synthesis 2011; 2011(04):653–61.
  9. Paleček J, Zweigerdt R, Olmer R, Martin U, Kirschning A, Dräger G. A practical synthesis of Rho-Kinase inhibitor Y-27632 and fluoro derivatives and their evaluation in human pluripotent stem cells. Org. Biomol. Chem. 2011; 9(15):5503–10.
  10. Berski S, van Bergeijk J, Schwarzer D, Stark Y, Kasper C, Scheper T, Grothe C, Gerardy-Schahn R, Kirschning A, Dräger G. Synthesis and biological evaluation of a polysialic acid-based hydrogel as enzymatically degradable scaffold material for tissue engineering. Biomacromolecules 2008; 9(9):2353–9.


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