REBIRTH Mitglieder

Kalies, Stefan

Kalies, Stefan, Dr. rer. nat.


REBIRTH Unit Biomedical Photonics for Regeneration Studies

NIFE – Niedersächsisches Zentrum für Biomedizintechnik, Implantatforschung und Entwicklung
Stadtfelddamm 34
30625 Hannover


Biography / About

Date of Birth:September, 1987
Function:Postdoc, Junior Research Group Leader: Unit 7.7 – Biomedical Photonics for Regeneration Studies


2007 - 2010Studies of physics,”Bachelor of Science”, Leibniz Universität Hannover
2010 - 2013Studies of physics,”Master of Science”, Leibniz Universität Hannover
09/2011 – 12/2011Internship, University of St. Andrews, St. Andrews, Scotland
10/2013 – 06/2016PhD student, Laser Zentrum Hannovere.V. / Hannover Biomedical ResearchSchool / REBIRTH Cluster of Excellence Hannover, Hannover

Academic appointments and Research posts:

03/2013 – 08/2015Research assistant, Laser Zentrum Hannover e.V., Hannover
09/2015 – 01/2016Research stay, Cornell University, Ithaca (US)
Since 03/2016Research assistant, Leibniz Universität Hannover (Institute of Quantum Optics), Hannover
Since 07/2016 Junior Research Group Leader, REBIRTH Cluster of Excellence Hannover, Hannover.Junior Research Group Leader of Unit 7.7 - Biomedical Photonics for RegenerationStudies

Awards and Prizes:

09/2015 - 01/2016Fulbright Scholarship, Research stay at Cornell University, Ithaca (US)
2015Second prize: Best Student Paper Award, Conference Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XV, Photonics West 2015, San Francisco

Major research interests:

  • Laser-based cell manipulation
  • Laser-tissue interactions
  • Imaging of regeneration
  • Nanostructures and particles
  • Cellular Biophysics

Selected Publications:

  1. Gentemann L, Kalies S, Coffee M, Meyer H, Ripken T, Heisterkamp A, Zweigerdt R, Heinemann D. Modulation of cardiomyocyte activity using pulsed laser irradiated gold nanoparticles. Biomed Opt Express. 2017; 8(1):177.
  2. Kalies S, Antonopoulos GC, Rakoski MS, Heinemann D, Schomaker M, Ripken T, Meyer H. Investigation of biophysical mechanisms in gold nanoparticle mediated laser manipulation of cells using a multimodal holographic and fluorescence imaging setup. PLoS One. 2015;10(4):e0124052.
  3. Kalies S, Keil S, Sender S, Hammer SC, Antonopoulos GC, Schomaker M, Ripken T, Murua Escobar H, Meyer H, Heinemann D. Characterization of the cellular response triggered by gold nanoparticle-mediated laser manipulation. J Biomed Opt. 2015; 20(11):115005.
  4. Kalies S, Heinemann D, Schomaker M, Murua Escobar H, Heisterkamp A, Ripken T, Meyer H. Plasmonic laser treatment for Morpholino oligomer delivery in antisense applications. J Biophotonics. 2014; 7(10):825–33.
  5. Heinemann D, Kalies S, Schomaker M, Ertmer W, Murua Escobar H, Meyer H, Ripken T. Delivery of proteins to mammalian cells via gold nanoparticle mediated laser transfection. Nanotechnology. 2014; 25(24):245101.
  6. Kalies S, Heinemann D, Schomaker M, Gentemann L, Meyer H, Ripken T. Immobilization of gold nanoparticles on cell culture surfaces for safe and enhanced gold nanoparticle-mediated laser transfection. J Biomed Opt. 2014; 19(7):70505.
  7. Kalies S, Gentemann L, Schomaker M, Heinemann D, Ripken T, Meyer H. Surface modification of silica particles with gold nanoparticles as an augmentation of gold nanoparticle mediated laser perforation. Biomed Opt Express. 2014; 5(8):2686.
  8. Kalies S, Birr T, Heinemann D, Schomaker M, Ripken T, Heisterkamp A, Meyer H. Enhancement of extracellular molecule uptake in plasmonic laser perforation. J Biophotonics. 2014; 7(7):474–82.
  9. Mitchell CA, Kalies S, Cizmar T, Heisterkamp A, Torrance L, Roberts AG, Gunn-Moore, FJ, Dholakia, K. Femtosecond optoinjection of intact tobacco BY-2 cells using a reconfigurable photoporation platform. PLoS One. 2013; 8(11):e79235.
  10. 1Kalies S, Kuetemeyer K, Heisterkamp A. Mechanisms of high-order photobleaching and its relationship to intracellular ablation. Biomed Opt Express. 2011; 2(4):805–16.

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