REBIRTH Members

Bauersachs, Johann

Bauersachs, Johann, Prof. Dr. med.

Head of Department

Department of Cardiology and Angiology Hannover Medical School


Carl-Neuberg-Str. 1
30625 Hannover

Bauersachs.Johann(at)mh-hannover.de

Biography / About

Date of Birth:April, 1966
Function:Full (W3) Professor and Head of Department of Cardiology and Angiology, MHH

Education:

1987 – 1993Studies of Medicine, University of Freiburg, Germany
12/1993Thesis (M.D.) at the University of Freiburg, Department of Physiology

Academic appointments and Research posts:

1993 - 1995Residency and Fellowship in Internal Medicine, University Hospital Frankfurt, Germany
1995 - 1996Postdoctoral/Research Associate, Physiology, University of Frankfurt
1996 - 1999Residency and Fellowship in Internal Medicine, University Hospital Mannheim, Germany
1999 - 2003Residency and Fellowship in Internal Medicine and Cardiology, Department of Medicine, University of Würzburg, Germany
1999 - 2004Scientific Secretary DFG Collaborative Research Centre (CRC) ‘SFB 355: Pathophysiology of Heart Failure’
2000Board Certification ‘Internal Medicine’
2001Habilitation, Member of the Faculty, senior lecturer, Department of Medicine, Division of Cardiology, University of Würzburg
2002Board Certification ‘Cardiology’
2006 - 2010Scientific Secretary DFG CRC ‘SFB 688 Mechanisms and Imaging of Cell-Cell-Interactions in the Cardiovascular System’
2008Board Certification ‘Intensive Care’
2008 - 2010Associate Professor, Department of Medicine I, University Hospital Würzburg
01/2010Call for W3-Professorship Cardiology/Angiology, University Hospital Giessen, Germany
Since 10/2010Full Professor and Head of Department, MHH

Other professional activities:

  • Speaker of the Clinical Research Unit (KFO) 311, ‘(Pre-)terminal heart and lung failure – mechanical unloading and repair’, funded by DFG
  • REBIRTH Cluster of Excellence, Member Steering Committee, Area Manager, DFG, Review Board Medicine, Chair, Cardiovascular Section
  • European Society of Cardiology, Fellow, Member Congress Program Committee (CPC), Heart Failure Association (HFA), Fellow, Board Member
  • Chair HFA Study Group Peripartum Cardiomyopathy; Former Chair, Working Group Myocardial Function
  • FP7 funded COST Action ADMIRE ‘AlDosterone and MIneralocorticoid REceptor: Pathophysiology, clinical implication and therapeutic innovations’, Management Committee

Awards and Prizes:

2001Oskar-Lapp-Award, “Deutsche Gesellschaft für Kardiologie“
2001Albert-Fraenkel-Award, „Deutsche Gesellschaft für Kardiologie“
2001Parmley-Award, American College of Cardiology
2001Bernard and Joahn Marshall Distinguished Investigator Award, British Society for Cardiovascular Research

Major research interests:

  • Left ventricular healing and remodelling
  • Acute and chronic heart failure
  • Peripartum cardiomyopathy
  • Aldosterone and mineralocorticoid receptor
  • Non-coding RNAs

Selected Publications:

  1. Bavendiek U, Aguirre Davila L, Koch A, Bauersachs J. Assumption versus evidence – the case of digoxin in atrial fibrillation and heart failure. Eur Heart J. 2017. DOI: dx.doi.org/10.1093/eurheartj/ehw577
  2. Bauersachs J, Arrigo M, Hilfiker-Kleiner D, Veltmann C, Coats AJ, Crespo-Leiro MG, De Boer RA, van der Meer P, Maack C, Mouquet F, Petrie MC, Piepoli MF, Regitz-Zagrosek V, Schaufelberger M, Seferovic P, Tavazzi L, Ruschitzka F, Mebazaa A, Sliwa K. Current management of patients with severe acute peripartum cardiomyopathy: practical guidance from the Heart Failure Association of the European Society of Cardiology Study Group on peripartum cardiomyopathy. Eur J Heart Fail. 2016. 18(9):1096-105. DOI: 10.1002/ejhf.586
  3. Zwadlo C, Schmidtmann E, Szaroszyk M, Kattih B, Froese N, Hinz H, Schmitto JD, Widder J, Batkai S, Bähre H, Kaever V, Thum T, Bauersachs J, Heineke J. Antiandrogenic therapy with finasteride attenuates cardiac hypertrophy and left ventricular dysfunction. Circulation. 2015. 131:1071-1081. DOI: 10.1161/CIRCULATIONAHA.114.012066.
  4. Hilfiker-Kleiner D, Haghikia A, Nonhoff J, Bauersachs J. Peripartum cardiomyopathy: current management and future perspectives. Eur Heart J. 2015. DOI: dx.doi.org 10.1093/eurheartj/ehv009
  5. Fraccarollo D, Berger S, Galuppo P, Kneitz S, Hein L, Schütz G, Frantz S, Ertl G, Bauersachs J. Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction. Circulation. 2011. 123(4):400-8. DOI: 10.1161/CIRCULATIONAHA.110.983023.
  6. Bauersachs J, Thum T. Biogenesis and regulation of cardiovascular microRNAs. Circ Res 109. 2011. 334-47. DOI: doi.org/10.1161/CIRCRESAHA.110.228676
  7. Thum T, Schmitter K, Fleissner F, Wiebking V, Dietrich B, Widder JD, Jazbutyte V, Hahner S, Ertl G, Bauersachs J. Impairment of endothelial progenitor cell function and vascularization capacity by aldosterone in mice and humans. Eur Heart J. 2011. 32(10):1275-86. DOI: 10.1093/eurheartj/ehq254.
  8. Thum T, Gross C, Fischer T, Fiedler J, Just S, Rottbauer W, Bussen M, Galuppo P, Frantz S, Castoldi M, Muckenthaler M, Soutschek J, Koteliansky V, Rosenwald A, Bauersachs J*, Engelhardt S* (*equal contribution). MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature. 2008. 456(7224):980-4. DOI: 10.1038/nature07511
  9. Fraccarollo D, Widder JD, Galuppo P, Thum T, Hoffmann M, Ruetten H, Ertl G, Bauersachs J. Improvement of left ventricular remodelling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction. Circulation. 2008. 118(8):818. DOI: doi.org/10.1161/CIRCULATIONAHA.107.717702
  10. Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, van Laake LW, Doevendans PA, Mummery CL, Borlak J, Haverich A, Gross C, Engelhardt S, Ertl G, Bauersachs J. MicroRNAs in the human heart: A clue to fetal gene reprogramming in heart failure. Circulation. 2007. 116(3):258-67. DOI: 10.1161/CIRCULATIONAHA.107.68794


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