REBIRTH Members

Ochs, Matthias

Ochs, Matthias, Prof. Dr. med.

Work Group Leader

REBIRTH Unit Quantitative Microscopy in Regeneration, Institut für Funktionelle und Angewandte Anatomie, Medizinische Hochschule Hannover


Biography / About

Date of Birth:December, 1967
Function:Full (W3) Professor and Head of the Institute of Functional and Applied Anatomy, Hannover Medical School (MHH)

Education:

1987 - 1994Studies and Graduation in Medicine, University of Göttingen, Germany
1998M.D., University of Göttingen (summa cum laude)
1999Specialist in anatomy, Lower Saxony Chamber of Physicians
2004Post-doctoral lecturing qualification (Habilitation) and venia legendi in anatomy, University of Bern, Switzerland

Academic appointments and Research posts:

1994 - 2002Scientific Assistant in anatomy, University of Göttingen
2002 - 2004Junior Professor of anatomy, University of Göttingen
2005 - 2009Lecturer and Associate Professor of anatomy, University of Bern
Since 2009Professor and Head, Institute of Functional and Applied Anatomy, MHH

Other professional activities:

Since 2007Member editorial board ‘Annals of Anatomy’
2007-2009Co-chairman task force ‘Quantitative assessment of lung structure’, American Thoracic Society
Since 2009Co-Director, Central Research Unit Electron Microscopy, MHH
Since 2011Member, section I (preclinical sciences), MHH
2011 - 2013Chairman, section I (preclinical sciences), MHH
Since 2012Member, REBIRTH steering committee
2012 - 2016Member, academic development committee and membership committee (chair 2015-2016), Fleischner Society for Thoracic Imaging and Diagnosis
2013 - 2015Member, MHH senate
Since 2015Chairman, section I (preclinical sciences), MHH
Since 2016Member editorial board ‘Histochemistry and Cell Biology’

Awards and Prizes:

1999Early Career Researcher Award (‘Nachwuchsförderpreis’), German Society for Thoracic & Cardiovascular Surgery
2003 - 2004Feodor Lynen Research Fellowship, Alexander von Humboldt Foundation: research stay at the Cardiovascular Research Institute, University of California, San Francisco, CA, USA
Since 2008Member elect, Fleischner Society for Thoracic Imaging and Diagnosis
2009Teacher of the year, Medical Faculty, University of Bern
2010/12/13/14/16Teaching awards, MHH
2011D.L.T. Smith visiting lecture, University of Saskatchewan, Saskatoon, Canada
Since 2012Adjunct Professor, Department of Veterinary Biomedical Sciences, University of Saskatchewan, Saskatoon, Canada

Major research interests:

  • Histology
  • Lung
  • Surfactant
  • Microscopy
  • Stereology

Furthermore:

Reviewer for various research institutions, societies, journals (incl. BBSRC/UK, CIHR/Canada, DFG/Germany, FWF/Austria, NRF/South Africa, SNF/Switzerland, Am J Physiol, Am J Respir Cell Mol Biol, Am J Respir Crit Care Med, Ann Anat, Eur Respir J, Histochem Cell Biol; J Clin Invest, Nat Protocols, N Engl J Med, Proc Natl Acad Sci USA, Sci Reports, Thorax, Trends Cell Biol); Teacher of stereology courses in Germany, Switzerland, USA, Brasil, South Africa, New Zealand; Member of American Thoracic Society.

Selected Publications:

  1. Grothausmann R, Knudsen L, Ochs M, Mühlfeld C. Digital 3D reconstructions using histological serial sections of lung tissue including the alveolar capillary network. American Journal of Physiology - Lung Cellular and Molecular Physiology. 2017. 312(2):L243.
  2. Ochs M, Knudsen L, Hegermann J, Wrede C, Grothausmann R, Mühlfeld C. Using electron microscopes to look into the lung. Histochem Cell Biol. 2016. 146:695-707.
  3. Kellner M, Heidrich M, Lorbeer RA, Antonopoulos GC, Knudsen L, Wrede C, Izykowski N, Grothausmann R, Jonigk D, Ochs M, Ripken T, Kühnel MP, Meyer H. A combined method for correlative 3D imaging of biological samples from macro to nano scale. Sci Reports. 2016. 6:35606.
  4. Lutz D, Gazdhar A, Lopez-Rodriguez E, Ruppert C, Mahavadi P, Günther A, Klepetko W, Bates JH, Smith B, Geiser T, Ochs M, Knudsen L. Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis. Am J Respir Cell Mol Biol. 2015. 52:232-243.
  5. Kellner M, Heidrich M, Beigel R, Lorbeer RA, Knudsen L, Ripken T, Heisterkamp A, Meyer H, Kühnel MP, Ochs M. Imaging of the mouse lung with scanning laser optical tomography (SLOT). J Appl Physiol. 2012. 113:975-983.
  6. Vasilescu DM, Gao Z, Saha PK, Yin L, Wang G, Haefeli-Bleuer B, Ochs M, Weibel ER, Hoffman EA. Assessment of morphometry of pulmonary acini in mouse lungs by non-destructive imaging using multi-scale micro-computed tomography. Proc Natl Acad Sci USA. 2012. 109:17105-17110.
  7. Vanhecke D, Herrmann G, Graber W, Hillmann T, Mühlfeld C, Studer D, Ochs M. Lamellar body ultrastructure revisited: high pressure freezing and cryo-electron microscopy of vitreous sections (CEMOVIS). Histochem Cell Biol. 2010. 134:319-326.
  8. Hsia CCW, Hyde DM, Ochs M, Weibel ER. An official research policy statement of the American Thoracic Society / European Respiratory Society: Standards for quantitative assessment of lung structure. Am J Respir Crit Care Med. 2010. 181:394-418.
  9. Mühlfeld C, Schaefer IM, Becker L, Bussinger C, Vollroth M, Bosch A, Nagib R, Madershahian N, Richter J, Wahlers T, Wittwer T, Ochs M. Pre-ischaemic exogenous surfactant reduces pulmonary injury in rat ischaemia/reperfusion. Eur Respir J. 2009. 33:625-633.
  10. Vanhecke D, Studer D, Ochs M. Stereology meets electron tomography: towards quantitative 3D electron microscopy. J Struct Biol. 2007. 159:443-450.


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