REBIRTH Members

Dräger, Gerald

Dräger, Gerald, Dr. rer. nat.

Work Group Leader

REBIRTH Unit Functionalized Polymers and Regenerative Agents

Leibniz University of Hannover, Institut für Organische Chemie
Schneiderberg 1b
30167 Hannover

draeger(at)oci.uni-hannover.de

Biography / About

Date of Birth:October, 1968
Function:Junior leader / academic director

Education:

1989 – 1997Technical University of Clausthal (Major: Organic Chemistry)
1994Diploma examination; “Synthese glycosylierter Decarestrictine” (Synthesis of glycosylated decarestrictins)
1997 Ph.D. examination, Advisor: Prof. Andreas Kirschning; „Synthesen desoxygenierter Glycokonjugate und Analoga” (Synthesis of deoxygenated glycoconjugates and analogues)

Academic appointments and Research posts:

1995 – 1996Research stay at the University of Göttingen, Institute of Organic Chemistry
1997 – 1998Postdoctorial position at the University of Washington, Department of Chemistry (Seattle, WA, USA), Advisor: Prof. Dr. H. G. Floss; ”Genetical and chemical exploration of the biosynthesis of the 2,6-dideoxyhexose moiety in granaticin”
Since 2000Independent research at the Institute of Organic Chemistry of the University Hannover (Germany) and head of the center for mass spectrometry

Other professional activities:

1999 – 2000Research chemist at the AnalytiCon AG in Potsdam/Berlin (Germany)
2009 – 2014CEO of the Centre of Biomolecular Drug Research (BMWZ)

Major research interests:

  • Hydrogels
  • Biopolymers
  • Surface chemistry
  • Nanoparticles
  • Small molecule synthesis

Selected Publications:

  1. Dibbert N, Krause A, Rios-Camacho J-C, Gruh I, Kirschning A, Dräger G. A Synthetic Toolbox for the In Situ Formation of Functionalized Homo- and Heteropolysaccharide-Based Hydrogel Libraries. Chemistry 2016; 22(52):18777–86.
  2. Dahlmann J, Krause A, Möller L, Kensah G, Möwes M, Diekmann A, Martin U, Kirschning A, Gruh I, Dräger G. Fully defined in situ cross-linkable alginate and hyaluronic acid hydrogels for myocardial tissue engineering. Biomaterials 2013; 34(4):940–51.
  3. Möller L, Hess C, Paleček J, Su Y, Haverich A, Kirschning A, Dräger G. Towards a biocompatible artificial lung: Covalent functionalization of poly(4-methylpent-1-ene) (TPX) with cRGD pentapeptide. Beilstein J Org Chem 2013; 9:270–7.
  4. Su Y, Paleček J, Kirschning A, Dräger G. Copper Mediated and Copper Free “Click” Decoration of Polysialic Acid for RGD-Modification and Hydrogel Formation. Macromol. Symp. 2013; 334(1):82–91.
  5. Krause A, Kirschning A, Dräger G. Bioorthogonal metal-free click-ligation of cRGD-pentapeptide to alginate. Org. Biomol. Chem. 2012; 10(29):5547–53.
  6. Möller L, Krause A, Bartsch I, Kirschning A, Witte F, Dräger G. Preparation and In Vivo Imaging of Lucifer Yellow Tagged Hydrogels. Macromol. Symp. 2011; 309-310(1):222–8.
  7. Möller L, Krause A, Dahlmann J, Gruh I, Kirschning A, Dräger G. Preparation and evaluation of hydrogel-composites from methacrylated hyaluronic acid, alginate, and gelatin for tissue engineering. IJAO 2011; 34(2):93–102.
  8. Paleček J, Dräger G, Kirschning A. A Practical Large-Scale Synthesis of Cyclic RGD Pentapeptides Suitable for Further Functionalization through ‘Click' Chemistry. Synthesis 2011; 2011(04):653–61.
  9. Paleček J, Zweigerdt R, Olmer R, Martin U, Kirschning A, Dräger G. A practical synthesis of Rho-Kinase inhibitor Y-27632 and fluoro derivatives and their evaluation in human pluripotent stem cells. Org. Biomol. Chem. 2011; 9(15):5503–10.
  10. Berski S, van Bergeijk J, Schwarzer D, Stark Y, Kasper C, Scheper T, Grothe C, Gerardy-Schahn R, Kirschning A, Dräger G. Synthesis and biological evaluation of a polysialic acid-based hydrogel as enzymatically degradable scaffold material for tissue engineering. Biomacromolecules 2008; 9(9):2353–9.


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