Field

Topic

Scientists

Reprogramming and Development

Identification of transcription factors required for self-renewal of ES cells

H. Schöler

Generation of oocytes from ES cells

H. Schöler

Reprogramming by ES cell fusion

H. Schöler

Nuclear transfer derived cloned mice

H. Schöler; M. Boiani

Telomere maintenance in reproductive cloning and mammalian development

K.L. Rudolph; H. Niemann

Nuclear transfer derived transgenic cattle and pigs

H. Niemann

Isolation of foetal and adult stem cells

H. Niemann

Expression of a Tetracycline sensitive system in transgenic pigs

H. Niemann; W. Kues

Mesodermal differentiation of rhesus monkey ES cells

K. Welte; U. Martin

Response of embryonic and adult haematopoietic stem cells to genetic programming

C. Baum

Signal transducers in development

M. Gaestel

Proteolytic pathways in cell cycle regulation

N. Malek

Analysis of transcriptional control and cell communication during organogenesis

A. Kispert; A. Gossler

Genetic causes of organ malformation

A. Kispert

Cellular dedifferentiation of endothelium, is linked to activation and silencing of certain nuclear transcription factors: Implications for endothelial dysfunction and vascular biology

J. Borlak

Neotendon formation in mesenchymal stem cells by manipulation of the Smad8 signalling pathway

G. Gross; A. Hoffmann

Haemato-lymphopoiesis and endothelium

Genetic causes of bone marrow failure

K. Welte; C. Klein

Cloning of and clinical long-term treatment with recombinant G-CSF

K. Welte

Role of EPO in endothelial regeneration

H. Haller

Identification of “stemness” genes by insertional mutagenesis

C. Baum

Telomere shortening limits haematopoiesis during ageing

K.L. Rudolph

Preclinical testing of telomerase therapies for liver regeneration

K.L. Rudolph

Cancer risk factors during regenerative failure in end stage disease (cirrhosis)

K.L. Rudolph

Identification of genes regulating dendritic cell differentiation

C. Klein

Role of chemokine receptors in lymphocyte homing and migration

R. Förster

Mechanisms of immune tolerance

G. Behrens; E. Jaeckel

The nature of diversity and diversification of the human MHC

R. Blasczyk

Regulating MHC expression

R. Blasczyk; A. Seltsam

Efficient gene transfer to hematopoietic stem cells in primates

P. A. Horn

In vivo selection of stem cells

P. A. Horn

First use of proteomics in clinical allogeneic hematopoietic stem cell transplantation

E. Weissinger; A. Ganser

Circulating endothelial cells as markers of endothelial damage in allogeneic stem cell transplantation

H. Haller; A. Ganser

Heart

Fist controlled clinical study of cell therapy in myocardial infarction

H. Drexler; A. Ganser; K. Wollert

First report on stem cell imaging after intracoronary transfer in patients with myocardial infarction

H. Drexler; K. Wollert

Understanding of potential contribution of adult and embryonic stem cells in myocardial regeneration

T. Kofidis; U. Martin

Generation and characterisation of functional cardiomyocytes from rhesus monkey ES-cells

U. Martin

Investigation of immunologal aspects of allogeneic intramyocardial ES-cell transplantation

T. Kofidis

In vivo application of engineered heart tissue based on ES-cell-derived cardiomyocytes

T. Kofidis

First clinical transplantation of tissue engineered heart valves

A. Haverich

Development an clinical application of biodegradable cardiovascular stents based on magnesium alloys

A. Haverich

Gene expression in distinct regions of the heart

J. Borlak 

Regulation of proangiogenic factor CCN1 in cardiac muscle: impact of ischemia, pressure overload, and neurohumoral activation

A. Hilfiker; D. Hilfiker-Kleiner; H. Drexler

STAT3 is required for myocardial capillary growth, control of interstitial matrix deposition, and protection of the heart from ischemic injury

H. Drexler; D. Hilfiker-Kleiner

Pivotal role of nitric oxide and oxidant stress for progenitor cell in vivo regenerative capacity

U. Land-messer; H. Drexler

Worldwide largest clinical programme for lung transplantation

A. Haverich

Worldwide first successful clinical use of an artificial lung (Novalung) as bridge to lung transplantation

S. Fischer; A. Haverich

Pivotal role of proteases in lung fibrosis

T. Welte

Demonstration of bone marrow-derived precursor cells in lung regeneration and fibrosis

H. Kreipe

Liver/pancreas

Clinical cell therapy using hepatocytes, novel cell application strategies for the treatment of metabolic liver disease

M. Ott; M. Manns

Regeneration in chronic hepatitis

M. Manns

Preclinical testing of telomerase therapies for liver regeneration

K.L. Rudolph

Cancer risk factors during regenerative failure in end stage disease (cirrhosis)

K.L. Rudolph

Role of oxidative stress and cytokines in beta cell death

S. Lenzen

Glucokinase glucose sensor function in insulin secretion

S. Lenzen

Development of large scale mouse mutagenesis

R. Balling

Human ES-cells: Assessment of culture related infection risks and contaminations

U. Martin

Experimental models and tools

In vivo microscopy of cell migration and intercellular interactions

M. Gunzer; D.J. Manstein

Quantitative and cell-specific assay to measure incorporation of donor cells into solid organs

H. Kreipe

Innovative integrating and episomal vectors for permanent and reversible cell modification, including delivery of siRNA

J. Bode; D. Wirth; H. Hauser; M. Scherr; M. Eder; C. Baum

Genetic instability in gene-modified cells, sencescence and cancer

S. Schlegel berger

Protein engineering, structure & design

D.J. Manstein

Epigenetic analysis in differentiation and cancer

H. Kreipe

Imaging, structure & functional analysis of individual molecules/molecular complexes

B. Brenner

Scaffold production and funtionalization, nanoengineering, laser technology

Production and functionalization of bioidentical, induced degradable biomatrices

A. Kirschning; P. Behrens; C. Grothe; T. Scheper

Bioidentical scaffolds made from polysialic acid

R. Gerardy-Schahn

Development of two-photon polymerization technique for the fabrication of arbitrary 3D structures

B.N. Chichkov

New mask-less nonlinear lithography for high-quality surface patterning

B.N. Chichkov

Surface nanostructuring using femtosecond laser pulses

A. Ostendorf, B. Chichkov

Waveguide structuring with fs-lasers

U. Morgner

Sub-µm ultrahigh resolution Optical Coherence Tomography

U. Morgner

Application of lasers and ultrafast optics in laser medicine and biomedical engineering

W. Ertmer

Application of ultrashort laser systems in clinical applications of medicine and cell biology

H. Lubatschowski

Development of optical tools for subcellular manipulation and imaging of submicron structures in living cells.

A. Heisterkamp

Generation of few-cycle-pulses

U. Morgner

Generation of intense high rep rate laser pulses

U. Morgner