Experimental models and tools

Text mining: powering the database revolution. Hahn U, Wermter J, Blasczyk R, Horn PA. Nature. 2007, Jul 12

Heat shock protein 70 (HSP70) induces cytotoxicity of T-helper cells. Figueiredo C, Wittmann M, Wang D, Dressel R, Seltsam A, Blasczyk R, Eiz-Vesper B. Blood.   2009, Mar 26

Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease. Jiang H, Schiffer E, Song Z, Wang J, Zürbig P, Thedieck K, Moes S, Bantel H, Saal N, Jantos J, Brecht M, Jenö P, Hall MN, Hager K, Manns MP, Hecker H, Ganser A, Döhner K, Bartke A, Meissner C, Mischak H, Ju Z, Rudolph KL. Proc Natl Acad Sci U S A. 2008, Aug 12

Going from genes to proteins in myelodysplastic syndromes.    Ganser A, Morgan MA, Weissinger EM.    Proc Natl Acad Sci U S A. 2007, Jan 23

The mechanism of pentabromopseudilin inhibition of myosin motor activity.    Fedorov R, Böhl M, Tsiavaliaris G, Hartmann FK, Taft MH, Baruch P, Brenner B, Martin R, Knölker HJ, Gutzeit HO, Manstein DJ. Nat Struct Mol Biol. 2009, Jan

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis. Gyrd-Hansen M, Darding M, Miasari M, Santoro MM, Zender L, Xue W, Tenev T, da Fonseca PC, Zvelebil M, Bujnicki JM, Lowe S, Silke J, Meier P. Nat Cell Biol. 2008 Nov

Scaffold expulsion and genome packaging trigger stabilization of herpes simplex virus capsids.    Roos WH, Radtke K, Kniesmeijer E, Geertsema H, Sodeik B, Wuite GJ. Proc Natl Acad Sci U S A. 2009 Jun 16

Native 3D intermediates of membrane fusion in herpes simplex virus 1 entry.    Maurer UE, Sodeik B, Grünewald K. Proc Natl Acad Sci U S A. 2008 Jul 29

Preventing and exploiting the oncogenic potential of integrating gene vectors.    Modlich U, Baum C. J Clin Invest. 2009, Apr

Guanine nucleotide-binding proteins of the G12 family shape immune functions by controlling CD4+ T cell adhesiveness and motility.    Herroeder S, Reichardt P, Sassmann A, Zimmermann B, Jaeneke D, Hoeckner J, Hollmann MW, Fischer KD, Vogt S, Grosse R, Hogg N, Gunzer M, Offermanns S, Wettschureck N. Immunity.   2009 May

Haemato-lymphopoiesis and endothelium

Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone.    Sorrentino SA, Bahlmann FH, Besler C, Müller M, Schulz S, Kirchhoff N, Doerries C, Horváth T, Limbourg A, Limbourg F, Fliser D, Haller H, Drexler H, Landmesser U.    Circulation. 2007, Jul 10

Engulfment of apoptotic cells by microvascular endothelial cells induces proinflammatory responses.    Kirsch T, Woywodt A, Beese M, Wyss K, Park JK, Erdbruegger U, Hertel B, Haller H, Haubitz M.    Blood.    2007, Apr 1

Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment.    Ju Z, Jiang H, Jaworski M, Rathinam C, Gompf A, Klein C, Trumpp A, Rudolph KL.    Nat Med.    2007, Jun

CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus.    Krueger A, Willenzon S, Lyszkiewicz M, Kremmer E, Förster R.    Blood.    2010, Mar 11

Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo.    Hammerschmidt SI, Ahrendt M, Bode U, Wahl B, Kremmer E, Förster R, Pabst O.    J Exp Med. 2008, Oct 27

Rapid leukocyte migration by integrin-independent flowing and squeezing.    Lämmermann T, Bader BL, Monkley SJ, Worbs T, Wedlich-Söldner R, Hirsch K, Keller M, Förster R, Critchley DR, Fässler R, Sixt M.    Nature    2008, May 1

Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.    Schlenk RF, Döhner K, Krauter J, Fröhling S, Corbacioglu A, Bullinger L, Habdank M, Späth D, Morgan M, Benner A, Schlegelberger B, Heil G, Ganser A, Döhner H; German-Austrian Acute Myeloid Leukemia Study Group.    N Engl J Med. 2008, May 1

Proteomic patterns predict acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Weissinger EM, Schiffer E, Hertenstein B, Ferrara JL, Holler E, Stadler M, Kolb HJ, Zander A, Zürbig P, Kellmann M, Ganser A.    Blood.    2007, Jun 15

Expression of the miR-17-92 polycistron in chronic myeloid leukemia (CML) CD34+ cells.    Venturini L, Battmer K, Castoldi M, Schultheis B, Hochhaus A, Muckenthaler MU, Ganser A, Eder M, Scherr M.    Blood.    2007, May 15

Endothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin therapy.    Sorrentino SA, Besler C, Rohrer L, Meyer M, Heinrich K, Bahlmann FH, Mueller M, Horváth T, Doerries C, Heinemann M, Flemmer S, Markowski A, Manes C, Bahr MJ, Haller H, von Eckardstein A, Drexler H, Landmesser U.    Circulation. 2010, Jan 5

The angiogenic factor CCN1 promotes adhesion and migration of circulating CD34+ progenitor cells: potential role in angiogenesis and endothelial regeneration.    Grote K, Salguero G, Ballmaier M, Dangers M, Drexler H, Schieffer B.    Blood. 2007 Aug 1

RAS and CSF3R mutations in severe congenital neutropenia.    Germeshausen M, Kratz CP, Ballmaier M, Welte K.    Blood. 2009, Oct 15

Neutrophil elastase is severely down-regulated in severe congenital neutropenia independent of ELA2 or HAX1 mutations but dependent on LEF-1.    Skokowa J, Fobiwe JP, Dan L, Thakur BK, Welte K.    Blood.    2009, Oct 1

Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras.    Ghosh A, Koestner W, Hapke M, Schlaphoff V, Länger F, Baumann R, Koenecke C, Cornberg M, Welte K, Blazar BR, Sauer MG.    Blood.    2009, Apr 30

In vivo expansion of cells expressing acquired CSF3R mutations in patients with severe congenital neutropenia. Germeshausen M, Welte K, Ballmaier M.    Blood.    2009, Jan 15

Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: Results of a long-term survey.    Germeshausen M, Ballmaier M, Welte K.    Blood.    2007, Jan 1

MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML.    Heuser M, Argiropoulos B, Kuchenbauer F, Yung E, Piper J, Fung S, Schlenk RF, Dohner K, Hinrichsen T, Rudolph C, Schambach A, Baum C, Schlegelberger B, Dohner H, Ganser A, Humphries RK.    Blood.    2007, Sep 1

High-affinity neurotrophin receptors and ligands promote leukemogenesis.    Li Z, Beutel G, Rhein M, Meyer J, Koenecke C, Neumann T, Yang M, Krauter J, von Neuhoff N, Heuser M, Diedrich H, Göhring G, Wilkens L, Schlegelberger B, Ganser A, Baum C.    Blood.    2009, Feb 26

Novel HAX1 mutations in patients with severe congenital neutropenia reveal isoform-dependent genotype-phenotype associations.    Germeshausen M, Grudzien M, Zeidler C, Abdollahpour H, Yetgin S, Rezaei N, Ballmaier M, Grimbacher B, Welte K, Klein C.    Blood. 2008, May 15

Naive B cells generate regulatory T cells in the presence of a mature immunologic synapse.    Reichardt P, Dornbach B, Rong S, Beissert S, Gueler F, Loser K, Gunzer M.    Blood.    2007 Sep 1

Multiple extra-thymic precursors contribute to T cell development with different kinetics.    Saran N, ?yszkiewicz M, Pommerencke J, Witzlau K, Vakilzadeh R, Ballmaier, M., von Boehmer H, Krueger A. Blood. 2009 Dec 15

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor.    Glocker EO, Kotlarz D, Boztug K, Gertz EM, Schäffer AA, Noyan F, Perro M, Diestelhorst J, Allroth A, Murugan D, Hätscher N, Pfeifer D, Sykora KW, Sauer M, Kreipe H, Lacher M, Nustede R, Woellner C, Baumann U, Salzer U, Koletzko S, Shah N, Segal AW, Sauerbrey A, Buderus S, Snapper SB, Grimbacher B, Klein C.    N Engl J Med.    2009, Nov 19

Novel genetic etiologies of severe congenital neutropenia.    Boztug K, Klein C.    Curr Opin Immunol.    2009, Oct

A syndrome with congenital neutropenia and mutations in G6PC3.    Boztug K, Appaswamy G, Ashikov A, Schäffer AA, Salzer U, Diestelhorst J, Germeshausen M, Brandes G, Lee-Gossler J, Noyan F, Gatzke AK, Minkov M, Greil J, Kratz C, Petropoulou T, Pellier I, Bellanné-Chantelot C, Rezaei N, Mönkemöller K, Irani-Hakimeh N, Bakker H, Gerardy-Schahn R, Zeidler C, Grimbacher B, Welte K, Klein C.    N Engl J Med.    2009, Jan 1

Heart and lung (incl. surgery, angiogenesis/arteriogenesis)

Development of the pacemaker tissues of the heart. Christoffels VM, Smits GJ, Kispert A, Moorman AF. Circ Res. 2010, Feb 5

Growth differentiation factor 15 for risk stratification and selection of an invasive treatment strategy in non ST-elevation acute coronary syndrome. Wollert KC, Kempf T, Lagerqvist B, Lindahl B, Olofsson S, Allhoff T, Peter T, Siegbahn A, Venge P, Drexler H, Wallentin L. Circulation. 2007, Oct 2

Prognostic value of growth-differentiation factor-15 in patients with non-ST-elevation acute coronary syndrome. Wollert KC, Kempf T, Peter T, Olofsson S, James S, Johnston N, Lindahl B, Horn-Wichmann R, Brabant G, Simoons ML, Armstrong PW, Califf RM, Drexler H, Wallentin L. Circulation. 2007, Feb 27

Economic implications of infections of implantable cardiac devices in a single institution. Kuehn C, Graf K, Heuer W, Hilfiker A, Chaberny IF, Stiesch M, Haverich A. Eur J Cardiothorac Surg. 2010, Apr

Engineering a novel three-dimensional contractile myocardial patch with cell sheets and decellularised matrix. Hata H, Bär A, Dorfman S, Vukadinovic Z, Sawa Y, Haverich A, Hilfiker A. Eur J Cardiothorac Surg. 2010, Mar 22

Biological materials in chest wall reconstruction: initial experience with the Peri-Guard Repair Patch. Wiegmann B, Zardo P, Dickgreber N, Länger F, Fegbeutel C, Haverich A, Fischer S. Eur J Cardiothorac Surg. 2010, Mar

Bronchial epithelial cells as a new source for differential transcriptome analysis after lung transplantation. Skawran B, Dierich M, Steinemann D, Hohlfeld J, Haverich A, Schlegelberger B, Welte T, von Neuhoff N. Eur J Cardiothorac Surg. 2009, Oct

Viable vascularized autologous patch for transmural myocardial reconstruction. Tudorache I, Kostin S, Meyer T, Teebken O, Bara C, Hilfiker A, Haverich A, Cebotari S. Eur J Cardiothorac Surg. 2009, Aug

Cardiac tissue engineering. Haverich A. Eur J Cardiothorac Surg. 2008, Aug

Myocardial tissue engineering: the extracellular matrix. Akhyari P, Kamiya H, Haverich A, Karck M, Lichtenberg A. Eur J Cardiothorac Surg. 2008, Aug

Evaluation of 188 consecutive homografts implanted in pulmonary position after 20 years. Boethig D, Goerler H, Westhoff-Bleck M, Ono M, Daiber A, Haverich A, Breymann T. Eur J Cardiothorac Surg. 2007, Jul

Evaluation of bromocriptine in the treatment of acute severe peripartum cardiomyopathy: a proof-of-concept pilot study. Sliwa K, Blauwet L, Tibazarwa K, Libhaber E, Smedema JP, Becker A, McMurray J, Yamac H, Labidi S, Struhman I, Hilfiker-Kleiner D. Circulation. 2010 Apr 6

Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction. Doerries C, Grote K, Hilfiker-Kleiner D, Luchtefeld M, Schaefer A, Holland SM, Sorrentino S, Manes C, Schieffer B, Drexler H, Landmesser U. Circ Res. 2007 Mar 30

A cathepsin D-cleaved 16 kDa form of prolactin mediates postpartum cardiomyopathy. Hilfiker-Kleiner D, Kaminski K, Podewski E, Bonda T, Schaefer A, Sliwa K, Forster O, Quint A, Landmesser U, Doerries C, Luchtefeld M, Poli V, Schneider MD, Balligand JL, Desjardins F, Ansari A, Struman I, Nguyen NQ, Zschemisch NH, Klein G, Heusch G, Schulz R, Hilfiker A, Drexler H. Cell. 2007 Feb 9

Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure. Heineke J, Auger-Messier M*, Xu J, Sargent M, York A, Welle S, Molkentin JD. Circulation. 2010 Jan 26

CIB1 is a novel regulator of pathological cardiac hypertrophy. Heineke J, Auger-Messier M, Correl RN, Xu J, Benard MJ, Yuan W, Parise LV, Drexler H, Molkentin JD. Nat Med. 2010.

MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, van Laake LW, Doevendans PA, Mummery CL, Borlak J, Haverich A, Gross C, Engelhardt S, Ertl G, Bauersachs J. Circulation. 2007, Jul 17

Limited efficacy of imatinib in severe pulmonary chronic graft-versus-host disease. Stadler M, Ahlborn R, Kamal H, Diedrich H, Buchholz S, Eder M, Ganser A. Blood. 2009, Oct 22

The Notch Ligand Delta-like 1 (Dll1) is Essential for Postnatal Arteriogenesis. Limbourg A., Ploom M., Elligsen D., Sörensen I., Ziegelhoeffer T., Gossler A., Drexler H. and Limbourg F. P. Circ. Res. 2007

Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia. Limbourg A, Korff T, Napp LC, Schaper W, Drexler H, Limbourg FP. Nat. Protoc. 2009

Liver/pancreas

Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection. Holdener M, Hintermann E, Bayer M, Rhode A, Rodrigo E, Hintereder G, Johnson EF, Gonzalez FJ, Pfeilschifter J, Manns MP, Herrath MG, Christen U. J Exp Med. 2008 Jun 9

An oncogenomics-based in vivo RNAi screen identifies new tumor suppressors in liver cancer Zender L, Xue W, Zuber J, Semighini CP, Krasnitz A, Ma, B, Zender P, Kubicka S, Luk JM, Schirmacher P, McCombie RW, Wigler M, Hicks J, Hannon GJ, Powers S, Lowe SW. Cell. 2008 Nov

Senescence of activated stellate cells limits liver fibrosis. Krizhanovsky V, Yon M, Dickins RA, Hearn S, Simon J, Miething C, Yee H, Zender L, Lowe SW. Cell. 2008 Aug 22

Telaprevir for previously treated chronic HCV infection. McHutchison JG, Manns MP, Muir AJ, Terrault NA, Jacobson IM, Afdhal NH, Heathcote EJ, Zeuzem S, Reesink HW, Garg J, Bsharat M, George S, Kauffman RS, Adda N, Di Bisceglie AM; PROVE3 Study Team. N Engl J Med. 2010 Apr 8

Argyrin a reveals a critical role for the tumor suppressor protein p27(kip1) in mediating antitumor activities in response to proteasome inhibition. Nickeleit I, Zender S, Sasse F, Geffers R, Brandes G, Sörensen I, Steinmetz H, Kubicka S, Carlomagno T, Menche D, Gütgemann I, Buer J, Gossler A, Manns MP, Kalesse M, Frank R, Malek NP. Cancer Cell. 2008, Jul 8

Reprogramming and Development, Stem Cell Biology

Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells Greber B, Wu G, Bernemann C, Joo JY, Han DW, Ko K, Tapia N, Sabour D, Sterneckert J, Tesar P, Schöler HR. Cell Stem Cell 2010, Mar

Direct reprogramming of human neural stem cells by OCT4. Kim JB, Greber B, Araúzo-Bravo MJ, Meyer J, Park KI, Zaehres H, Schöler HR. Nature 2009, Oct

Induction of pluripotency in adult unipotent germline stem cells. Ko K, Tapia N, Wu G, Kim JB, Bravo MJ, Sasse P, Glaser T, Ruau D, Han DW, Greber B, Hausdörfer K, Sebastiano V, Stehling M, Fleischmann BK, Brüstle O, Zenke M, Schöler HR. Cell Stem Cell 2009, Jul

Oct4-induced pluripotency in adult neural stem cells. Kim JB, Sebastiano V, Wu G, Araúzo-Bravo MJ, Sasse P, Gentile L, Ko K, Ruau D, Ehrich M, van den Boom D, Meyer J, Hübner K, Bernemann C, Ortmeier C, Zenke M, Fleischmann BK, Zaehres H, Schöler HR. Cell 2009, Feb

Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Kim JB, Zaehres H, Wu G, Gentile L, Ko K, Sebastiano V, Araúzo-Bravo MJ, Ruau D, Han DW, Zenke M, Schöler HR. Nature 2008, Jul

Absence of OCT4 expression in somatic tumor cell lines. Cantz T, Key G, Bleidissel M, Gentile L, Han DW, Brenne A, Schöler HR. Stem Cells. 2008, Mar

Induction of pluripotency: from mouse to human. Zaehres H, Schöler HR. Cell 2007, Nov

Genome-wide expression profiling reveals distinct clusters of transcriptional regulation during bovine preimplantation development in vivo. Kues WA, Sudheer S, Herrmann D, Carnwath JW, Havlicek V, Besenfelder U, Lehrach H, Adjaye J, Niemann H. Proc Natl Acad Sci U S A. 2008, Dec 16

NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway. Skokowa J, Lan D, Thakur BK, Wang F, Gupta K, Cario G, Brechlin AM, Schambach A, Hinrichsen L, Meyer G, Gaestel M, Stanulla M, Tong Q, Welte K. Nat Med. 2009, Feb

HOXB4's road map to stem cell expansion. Schiedlmeier B, Santos AC, Ribeiro A, Moncaut N, Lesinski D, Auer H, Kornacker K, Ostertag W, Baum C, Mallo M, Klump H. Proc Natl Acad Sci U S A. 2007, Oct 23

Systemic deficiency of the MAP kinase-activated protein kinase 2 reduces atherosclerosis in hypercholesterolemic mice. Jagavelu K, Tietge UJ, Gaestel M, Drexler H, Schieffer B, Bavendiek U. Circ Res. 2007, Nov 26

The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Benedito R, Roca C, Sörensen I, Adams S, Gossler A, Fruttiger M, Adams RH. Cell. 2009, Jun 12

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries. Sörensen I, Adams RH, Gossler A. Blood. 2009, May 28

Angiopoietin-2 predicts disease-free survival after allogeneic stem cell transplantation in patients with high-risk myeloid malignancies. Kümpers P, Koenecke C, Hecker H, Hellpap J, Horn R, Verhagen W, Buchholz S, Hertenstein B, Krauter J, Eder M, David S, Göhring G, Haller H, Ganser A. Blood. 2008, Sep 1

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation. Choudhury AR, Ju Z, Djojosubroto MW, Schienke A, Lechel A, Schaetzlein S, Jiang H, Stepczynska A, Wang C, Buer J, Lee HW, von Zglinicki T, Ganser A, Schirmacher P, Nakauchi H, Rudolph KL. Nat Genet. 2007, Jan

Generation of induced pluripotent stem cells from human cord blood. Haase, A., Olmer, R., Schwanke, K., Wunderlich, S., Merkert, S., Hess, C., Zweigerdt, R., Gruh, I., Meyer, J., Wagner, S., Maier, L.S., Han, D.W., Glage, S., Miller, K., Fischer, P., Scholer, H.R., and Martin, U. Cell Stem Cell 2009, Oct

Generation of functional murine cardiac myocytes from induced pluripotent stem cells. Mauritz, C., Schwanke, K., Reppel, M., Neef, S., Katsirntaki, K., Maier, L.S., Nguemo, F., Menke, S., Haustein, M., Hescheler, J., Hasenfuss, G., and Martin, U. Circulation 2008

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways. Kustikova OS, Geiger H, Li Z, Brugman MH, Chambers SM, Shaw CA, Pike-Overzet K, de Ridder D, Staal FJ, von Keudell G, Cornils K, Nattamai KJ, Modlich U, Wagemaker G, Goodell MA, Fehse B, Baum C. Blood. 2007, Mar 1

MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells. Schwermann J, Rathinam C, Schubert M, Schumacher S, Noyan F, Koseki H, Kotlyarov A, Klein C, Gaestel M. EMBO J. 2009, May 20

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Cheng HT, Kim M, Valerius MT, Surendran K, Schuster-Gossler K, Gossler A, McMahon AP, Kopan R. Development. 2007, Feb

Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse. Trowe MO, Shah S, Petry M, Airik R, Schuster-Gossler K, Kist R, Kispert A. Dev Biol. 2010, Mar 24

Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse. Zirzow S, Lüdtke TH, Brons JF, Petry M, Christoffels VM, Kispert A. Dev Biol. 2009, Dec 15

Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice Schaetzlein S, Kodandaramireddy NR, Ju Z, Lechel A, Stepczynska A, Lilli DR,Clark AB, Rudolph C, Kuhnel F, Wei K, Schlegelberger B, Schirmacher P, Kunkel TA,Greenberg RA, Edelmann W, Rudolph KL. Cell. 2007 Sep 7

Non-cyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation. Feller J, Schneider A, Schuster-Gossler K, Gossler A. Genes Dev. 2008, Aug 15

A changing genetic hierarchy regulates morphogenesis in three regions of the mouse notochord. Yamanaka Y., Tamplin O.J., Beckers A., Gossler A., and Rossant J. Dev. Cell 2007

Tbx18 and the fate of epicardial progenitors. Christoffels VM, Grieskamp T, Norden J, Mommersteeg MT, Rudat C, Kispert A. Nature. 2009, Apr 16

A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14. Bohn G, Allroth A, Brandes G, Thiel J, Glocker E, Schäffer AA, Rathinam C, Taub N, Teis D, Zeidler C, Dewey RA, Geffers R, Buer J, Huber LA, Welte K, Grimbacher B, Klein C. Nat Med. 2007, Jan

HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease). Klein C, Grudzien M, Appaswamy G, Germeshausen M, Sandrock I, Schäffer AA, Rathinam C, Boztug K, Schwinzer B, Rezaei N, Bohn G, Melin M, Carlsson G, Fadeel B, Dahl N, Palmblad J, Henter JI, Zeidler C, Grimbacher B, Welte K. Nat Genet. 2007, Jan

The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning. Beckers A, Alten L, Viebahn C, Andre P, Gossler A. Proc Natl Acad Sci U S A. 2007, Oct 2

Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants. Schuster-Gossler K, Cordes R, Gossler A. Proc Natl Acad Sci U S A. 2007, Jan 9

Wt1 and Retinoic Acid Signaling in the Subcoelomic Mesenchyme Control the Development of the Pleuropericardial Membranes and the Sinus Horns. Norden J, Grieskamp T, Lausch E, van Wijk B, van den Hoff MJ, Englert C, Petry M, Mommersteeg MT, Christoffels VM, Niederreither K, Kispert A. Circ Res. 2010, Feb 25

Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canal. Singh R, Horsthuis T, Farin HF, Grieskamp T, Norden J, Petry M, Wakker V, Moorman AF, Christoffels VM, Kispert A. Circ Res. 2009, Aug 28

Scaffold production and funtionalization, nanoengineering, laser technology

Fs-laser-induced Ca2+ concentration change during membrane perforation for cell transfection. Baumgart J, Bintig W, Ngezahayo A, Lubatschowski H, Heisterkamp A. Opt Express. 2010 Feb 1

Repetition rate dependency of reactive oxygen species formation during femtosecond laser-based cell surgery. Baumgart J, Kuetemeyer K, Bintig W, Ngezahayo A, Ertmer W, Lubatschowski H, Heisterkamp A. J Biomed Opt. 2009 Sep-Oct

Repetition rate dependency of lowdensity plasma effects during femtosecond-laser-based surgery of biological tissue K. Kuetemeyer, J. Baumgart, H. Lubatschowski, A. Heisterkamp Appl. Phys. 2009

Computational model for nonlinear plasma formation in high NA micromachining of transparent materials and biological cells. Arnold CL, Heisterkamp A, Ertmer W, Lubatschowski H. Opt Express. 2007 Aug 6

Quantified femtosecond laser based opto-perforation of living GFSHR-17 and MTH53 a cells. Baumgart J, Bintig W, Ngezahayo A, Willenbrock S, Murua Escobar H, Ertmer W, Lubatschowski H, Heisterkamp A. Opt Express. 2008 Mar 3

Two-photon fabrication Farsari M, Chichkov BN Nature Photonics. 2009

Three dimensional microstructuring of biopolymers by femtosecond laser irradiation Oujja M, Perez S, Fadeeva E, Koch J, Chichkov BN, Castillejo M Appl. Phys. Lett. 2009